Rosetta MCP Server

Author: Ariel J. Ben-Sasson A Model Context Protocol (MCP) server that lets Cursor (or any MCP client) work with Rosetta, PyRosetta, and Biotite: run RosettaScripts, validate XML protocols, translate between Rosetta and Biotite, score structures, and query documentation -- all from your AI coding assistant. It runs locally over stdio via the published package.

People connecting coding agent tools to Claude, Cursor, VS Code, or another MCP client. The project is written in JavaScript.

VERIFIED ACTIVE

LAST COMMIT 2026-04-05 · ★ 18 · #124 OF 194 MAINTAINED CODING AGENT · VERIFIED 2026-08-25

JavaScript servers · how we verify → /methodology

01 · Install Rosetta MCP Server

before you install - you'll need

ROSETTA_BIN, PYTHON_BIN are optional or environment-specific per the README.

Claude Code

claude mcp add arielbs-rosetta-mcp-server -- npx -y rosetta-mcp-server

Claude Desktop / Cursor / VS Code - add to config

{
  "mcpServers": {
    "arielbs-rosetta-mcp-server": {
      "command": "npx",
      "args": [
        "-y",
        "rosetta-mcp-server"
      ]
    }
  }
}

Same JSON for Cursor. For VS Code, rename the top-level key from `mcpServers` to `servers`.

Using another client? Same JSON, different key

Claude Desktop · mcpServers

Cursor · mcpServers

VS Code · servers

Windsurf · mcpServers

Zed · context_servers

Cline · mcpServers

Roo Code · mcpServers

Continue · mcpServers

LibreChat · mcpServers

Gemini CLI · mcpServers

Codex CLI · mcp_servers

Full setup guides: every client.

02 · Evidence

Security posture

What to check before giving this server access to your agent - from the registry, GitHub, and our own probes. We don't score safety; we show what's verifiable.

runs as local process (stdio) - runs on your machine with your user's permissions

license no standard license detected - usage rights unclear; check the repo before commercial use

npm package rosetta-mcp-server - unscoped; check the name against the project README before installing

registry namespace io.github.Arielbs is GitHub-verified and matches the repo owner

03 · Who maintains Rosetta MCP Server

rosetta-mcp-server is maintained by arielbs. It's the only MCP server we track from this author; the repo dates to Aug 2025.

04 · Facts

repository: github.com/arielbs/rosetta-mcp-server
category: coding agent - ranked #124 of 194 actively-maintained coding agent servers as of 2026-08-25.
registry: io.github.Arielbs/rosetta-mcp-server (active, first published 2026-04-03)
packages: npm:rosetta-mcp-server

05 · Rosetta MCP Server FAQ

What is Rosetta MCP Server?

Is Rosetta MCP Server still maintained?

Yes - as of 2026-08-25, its last commit was 2026-04-05. We re-verify nightly.

How do I install Rosetta MCP Server?

Run `npx -y rosetta-mcp-server`. The README documents 2 environment variables (ROSETTA_BIN, PYTHON_BIN) to set first. ROSETTA_BIN, PYTHON_BIN are optional or environment-specific per the README. You can also paste the ready-made client config above.

Does Rosetta MCP Server run locally?

Yes - it's a stdio server: it runs on your machine (via npx) with your user's permissions. Your data stays local unless the server itself calls external APIs.

06 · Alternatives to Rosetta MCP Server

Alternatives to Rosetta MCP Server

Maintained coding agent servers if Rosetta MCP Server isn't the fit.

Pairs well with

Servers that cover what Rosetta MCP Server doesn't - only shown when the pairing reason fits the companion.

More coding agent MCP servers · Eu AI Act · Dvalincode · Agent Never Give Up · Roseline MCP · Parecode

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