Appendix MCP Server
Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one. Its 3 documented tools cluster into read & search, submit. It is available as a remote MCP endpoint.
Teams that want a hosted science & health endpoint instead of running a local process. The project is written in TypeScript.
VERIFIED ACTIVE
LAST COMMIT 2026-06-12 · ★ 2 · #58 OF 60 MAINTAINED SCIENCE & HEALTH · VERIFIED 2026-08-25
TypeScript servers · how we verify → /methodology
01 · Install Appendix
Claude Code
claude mcp add appendixhealth-mcp-server --transport http https://mcp.appendix.com/mcp Claude Desktop / Cursor / VS Code - add to config
{
"mcpServers": {
"appendixhealth-mcp-server": {
"url": "https://mcp.appendix.com/mcp"
}
}
} Same JSON for Cursor. For VS Code, rename the top-level key from `mcpServers` to `servers`.
Using another client? Same JSON, different key
Claude Desktop · mcpServers
Cursor · mcpServers
VS Code · servers
Windsurf · mcpServers
Zed · context_servers
Cline · mcpServers
Roo Code · mcpServers
Continue · mcpServers
LibreChat · mcpServers
Gemini CLI · mcpServers
Codex CLI · mcp_servers
Full setup guides: every client.
02 · Evidence
https://mcp.appendix.com/mcp
transport: streamable-http
endpoint alive - responded to MCP initialize · probed 2026-08-25
Security posture
What to check before giving this server access to your agent - from the registry, GitHub, and our own probes. We don't score safety; we show what's verifiable.
runs as remote - your agent's requests go to mcp.appendix.com
endpoint auth accepted our unauthenticated MCP initialize - no credentials needed to connect
license no standard license detected - usage rights unclear; check the repo before commercial use
registry vendor namespace com.appendix - domain-verified with the official MCP registry
03 · What Appendix can do
Prose above is summarized from the project's README and registry record - no invented capabilities.
What you can build
With this server connected, an agent can search medical literature and treatment guidelines, and list available conditions and medications.
The 3 tools it gives your agent
Extracted from the project's README - what Appendix lets an agent do.
- search_knowledge_base
- - Search medical literature and treatment guidelines
- submit_encounter
- - Submit a clinical letter for physician review
- list_conditions
- - List available conditions and medications
04 · Who maintains Appendix
Appendix is maintained by appendixhealth. It's the only MCP server we track from this author; the repo dates to May 2026.
05 · Facts
- repository
- github.com/appendixhealth/mcp-server
- website
- https://appendix.com/
- category
- science & health - ranked #58 of 60 actively-maintained science & health servers as of 2026-08-25.
- registry
- com.appendix/appendix (active, first published 2026-06-02)
06 · Appendix FAQ
Is Appendix still maintained?
Yes - as of 2026-08-25, its last commit was 2026-06-12. We re-verify nightly.
What can Appendix do?
With this server connected, an agent can search medical literature and treatment guidelines, and list available conditions and medications.
How do I install Appendix?
Run `claude mcp add appendixhealth-mcp-server --transport http https://mcp.appendix.com/mcp`. You can also paste the ready-made client config above.
Does Appendix require authentication?
No - the endpoint accepted our unauthenticated MCP initialize when probed on 2026-08-25; you can connect without credentials.
07 · Alternatives to Appendix
Alternatives to Appendix
Maintained science & health servers if Appendix isn't the fit.
- Arxiv MCP Server (blazickjp) Search arXiv papers, download full text, semantic search, citation graphs, and alerts via MCP. ★ 3,071 · 2026-08-24
- Paper Banana Generate academic diagrams and statistical plots from text using multi-agent AI. ★ 2,279 · 2026-08-17
- Pyscn Python code analysis for AI agents: complexity, dead code, clones, coupling, and a health score. ★ 1,035 · 2026-08-25
- Pubmed MCP Server Search PubMed/Europe PMC, fetch articles and full text (PMC/EPMC/Unpaywall), citations, MeSH terms. ★ 137 · 2026-08-21
- FHIR MCP Server MCP server providing seamless access to FHIR APIs for AI tools and healthcare applications ★ 132 · 2026-07-14
- Clinicaltrialsgov MCP Server Search ClinicalTrials.gov - find studies, retrieve results, match patients to eligible trials. ★ 90 · 2026-08-21
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